https://www.mcbridelab.org/video-gallery daily 0.75 2021-07-28 https://www.mcbridelab.org/video-gallery/soul-dn89m monthly 0.5 2021-07-28 https://www.mcbridelab.org/video-gallery/summer-retreat-2dkh4 monthly 0.5 2021-07-28 https://www.mcbridelab.org/video-gallery/yoga-pxnbs monthly 0.5 2021-07-28 https://www.mcbridelab.org/video-gallery/exploring-npn3a monthly 0.5 2021-07-28 https://www.mcbridelab.org/about-heidi daily 0.75 2023-01-12 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/2b3eb49b-c549-40ec-8345-0a69290fb510/heidi_bio_pic.jpg About Heidi - Heidi McBride, Ph.D, FRSC Canada Research Chair in Mitochondrial Cell Biology Professor, McGill University Montreal Neurological Institute Neuromuscular Research Group 3801 University Ave, Rm 622C Montreal, Quebec H3A 2B4 heidi.mcbride@mcgill.ca (514) 398-1808 Twitter: @mitodynamics https://www.mcbridelab.org/team daily 0.75 2025-08-18 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1627497596489-YD7QKMKIUFY8EKW11E1J/vanessa.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643164679809-FLJSA5H6IFANKFY2N5I8/photo%252Bcamila.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643164850499-CKAM49JWEFONZCDWU86G/andres.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643164983385-VL45Y5HBPGS7GFAZET1O/mai.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/bdb7dde1-fade-4366-980a-b0c10d8b138f/1586805818558.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/fd04ad6a-e742-4a87-836a-84009e8844ec/Jess+Wolf.jpg Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/f3e42bbd-ab42-47cf-8eb1-5d13819be88d/image+%281%29.png Team https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/3f3da37e-236b-4b46-a51b-c4e4723a3a41/Yeji_Song.JPG Team https://www.mcbridelab.org/research daily 0.75 2023-01-12 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/6bee0a9b-62c0-4fef-818c-8a20f0b1d3d4/Screen+Shot+2021-11-06+at+7.35.46+PM.png Research - 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Research Associate A native of Argentina, Rodolfo has been a Research Associate in the lab since 2001. He has worked on almost all projects, but he focuses on the role of SUMOylation in mitochondrial dynamics and signaling. Rudi is a senior, valued and trusted leader in the group. Expertise: rodolfo.zunino@mcgill.ca https://www.mcbridelab.org/mai daily 0.75 2022-01-17 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631757087317-ITHP10OKZ4JYRC1CU8UW/mai.jpg Mai - Research Associate Mai joined as a Research Associate after a successful tenure in the lab of Gordon Shore (McGill). Mai has researched mitochondria throughout her career, from transcriptional pathways to protein import, cell death, cancer, and the development of therapeutics. In Dr. McBride's laboratory, her goal is to uncover the signaling pathways that couple mitochondrial sumo ligase MAPL to cellular responses. She recently discovered some key components that potentially link lysosomal damage response to mitochondrial dysfunction. Mai's strength is her commitment to teamwork. She readily embraces expertise from new lab members and enjoys the interaction at all levels Expertise: mai.nguyen@mcgill.ca https://www.mcbridelab.org/vanessa daily 0.75 2022-01-19 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631756891731-IOXEHY5NT30GGBHGT6PT/vanessa.jpeg Vanessa - Research Associate Vanessa trained in Bordeaux studying mitochondrial respiration before joining the lab in 2009 as a post-doctoral fellow. Now a Research Associate, Vanessa has revolutionized the scope of the lab with her use of animal models to study the role of SUMOylation in cell signaling, cell fate, and of course – mitochondrial function. There are surprising things coming soon from Vanessa!! vanessa.goyon@mcgill.ca Expertise: https://www.mcbridelab.org/akihiro daily 0.75 2021-09-16 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631757301566-YI7OSMSNKSCRPX4J786H/Akihiro-1.jpeg Akihiro - Graduate Student Ph.D. student. Hailing from northern Japan, Akihiro joined us after completing his M.Sc. from the University of Tokyo where he demonstrated that plant mitochondria also generate MDVs. He is continuing his Ph.D. work with us examining the function of steady-state MDV transport to peroxisomes. The links between mitochondria and peroxisomes will continue to be uncovered under the watchful eye of Aki! Expertise: akihiro.yamashita@mail.mcgill.ca https://www.mcbridelab.org/tim daily 0.75 2021-09-16 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631761840732-5SMPHQPP7L811AKJK5VL/Tim-1-300x300.jpeg Tim - Post-Doctoral Fellow Tim obtained his Ph.D. in the lab of Thomas Langer at the University of Koln, after a short internship with Christian Ungermann at the University of Osnabruck, Germany. A highly skilled biochemist with experience in membrane trafficking, the contribution of mitochondrial proteases to calcium signaling, and more. In our lab, Tim is tackling the molecular mechanism of mitochondrial vesicle formation and cargo selection. A challenging project, Tim does not shy away from complexity and is using our established assay systems, along with his own creative, newly designed assays and tools to crack this important problem. tim.konig@mcgill.ca https://www.mcbridelab.org/aurele daily 0.75 2022-01-17 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631761967259-ZBZ89C34QTPINGDHHKSN/aurele-copy-284x300.jpeg Aurèle - Post-Doctoral Fellow Aurèle joined us after a stellar Ph.D in the lab of Jennifer Estall at the IRCM where he worked on the pathogenesis of diabetes, focusing on the role of transcriptional coactivators in liver. A native of France, Aurèle gained a profound knowledge of global metabolism during his training. He is currently working to understand how the peroxisome contribute to metabolic homeostasis at both the cellular and organismal level. Often overlooked, peroxisome dynamics, biogenesis and function have captured Aurèle’s imagination and he wants to unlock new paradigm in our understanding of peroxisomes by combining his previous expertise with the tricks of the McBride lab. Expertise: Liver, glucose homeostatis, sex differences, peroxisomes, mouse physiology aurele.besse-patin@mcgill.ca https://www.mcbridelab.org/dhaval daily 0.75 2021-09-16 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1629300578609-8HXSIKBWN2ODS45QKTNE/dhaval.jpeg Dhaval - Post-Doctoral Fellow Coming to us from the exciting metropolis of Mumbai, Dhaval completed his Ph.D. in the lab of Stephen Witt at Louisiana State University in Shreveport where he utilized yeast models to uncover the function of sorting nexins in the trafficking of iron transporters. He also explored yeast as a model to examine the role of alpha-synuclein in endosomal trafficking pathways. He joined us to continue our work on the mechanisms of iron delivery to mitochondria, in a project initiated by Maxime Jacoupy. His interest in the role of Parkinson’s related proteins in these pathways remains keen and we look forward to the many new truths he will uncover. Expertise: dhaval.n.patel@mcgill.ca https://www.mcbridelab.org/andres daily 0.75 2022-01-21 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1631762242772-6NCZZK91PJTO2H0DDJUS/andres.jpeg Andres - Post-Doctoral Fellow Native from Montevideo Uruguay, I completed my PhD studies in the lab of Prof. Atan Gross, where I studied the role of the mitochondrial protein MTCH2 in regulating the morphology and dynamic behavior of this organelle. During my period in the Weizmann Institute, I specialized in microscopy, image analysis and biochemistry, navigating through the fields of mitochondrial dynamics, but also areas such as apoptosis, mitochondrial DNA homeostasis, inter-organelle contact sites, mitochondrial function as well as metabolism and lipids homeostasis. Now in Heidi’s lab my focus will be to study one of the most, if not the most important biological function for which mitochondria are critical and essential for. This important task that only mitochondria can mediate is the forging of iron into bioactive molecules. Although the biochemical steps and enzymes necessary for iron-sulfur clusters and heme biosynthesis are well characterized, how iron gets to the mitochondria and how this delivery is modulated remains a big gap in the knowledge of mitochondrial iron metabolism. Integrating screening data and monitoring the iron status of the mitochondria and the cell I plan to shed new light on the ancient and essential mechanism of iron delivery into the mitochondria. Expertise: mitochondrial dynamics, iron transport, contact sites andres.goldman@mcgill.ca https://www.mcbridelab.org/jack daily 0.75 2022-01-26 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/4e5432be-1d2c-4300-905c-25d476f0e60a/IMG_91DFF1731B9D-1.jpg Jack - Post-Doctoral Fellow Jack studied Biomedical Genetics for his undergraduate degree at Newcastle University. His PhD project then involved researching rare neurological diseases at the Wellcome Centre for Mitochondrial Research at Newcastle University, primarily focussing on characterising a novel neurodevelopmental disorder caused by impaired autophagy. During this time, Jack was awarded an EMBO Short-term Fellowship at the University of Helsinki where he used induced pluripotent stem cells and differentiated neural culture to further uncover how defective autophagy impairs neural integrity. Now an EMBO Postdoctoral Fellow, Jack’s training continues in the McBride Lab where he moves to uncover how Parkinson’s disease-related proteins regulate innate and adaptive immunity in response to inflammation. Expertise: Neurological disease, autophagy, intracellular trafficking jack.collier@mail.mcgill.ca https://www.mcbridelab.org/teaching daily 0.75 2022-01-26 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1629299760036-FGVHHOE3BGRDLANC127U/celltraffic.jpeg Teaching I co-ordinate and teach “ANAT365: Cellular Trafficking”, a third-year undergraduate course in the Department of Anatomy and Cell Biology. The McGill link to the course is below: https://www.mcbridelab.org/publications daily 0.75 2022-01-26 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643224013386-BB2VUN4VEN8OYH41FJ9Y/Paper2.png Publications https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643224038805-66HC67WJ94VINDH18K3U/Paper1.png Publications https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643224062374-C8OHMROPE8YDMR3XVWZW/Paper3.png Publications https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643224104482-HI5TQHDVA4GY6NVVC5AO/Paper4.png Publications https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643224137887-0V9DG0QXGJ2NI0YM7W5O/Paper5.png Publications https://www.mcbridelab.org/mt-fusion daily 0.75 2022-01-25 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1642202793223-XULAF7SMT4E6ESJHKT6A/golgi%2Bat%2Bfission%2Bsite.jpg MT fusion https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/e7b2d96d-7a29-4e30-a769-d30313f88910/Sevan+model.png MT fusion https://www.mcbridelab.org/mt-fission-and-signaling daily 0.75 2022-01-15 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/5b66dd02-b728-4e4b-b8ed-28d5c69b980d/Julien+death+SUMO+model.png MT fission and signaling https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/f20800e5-a1e1-4cd6-a3c6-13de27a4bbae/sumo+yfp+death.jpg MT fission and signaling https://www.mcbridelab.org/mt-derived-vesicles daily 0.75 2022-01-26 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643226718006-CR43SYWK3U5XT3GR8ZZC/MDVPaper1.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643226783044-UERYZQSCL3H8RYHEF91H/MDVpaper4.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643227076626-A4EZ1OX3MAD2GP1QB7NC/Paper2.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643227942883-DRKOMTV2NSPFXS7MZJ9H/MDVpaper2.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/8977076d-08c5-4505-a3f0-93217a4681a8/Konig_Cover_Art_1_green_magenta.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/e5505429-7911-4cd0-a381-3d8b5fb05257/Konig_Cover_Art_1_magenta_cyan.png MT derived vesicles https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/55641285-9797-4bba-be75-fc1bfed555be/Konig_Cover_Art_1_orange_cyan.png MT derived vesicles https://www.mcbridelab.org/olesia daily 0.75 2023-01-13 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/83140076-d844-475a-b7e7-5b351b6d65e9/Screen+Shot+2022-01-17+at+12.51.43+PM.jpg Olesia - Post-Doctoral Fellow Mesmerized by all things biology, Olesia received her original training in genetics and cell biology, using drosophila as a model organism. She then completed her PhD studies in the Suomalainen lab at the University of Helsinki, Finland, supported by scholarships from the Doctoral Program in Biomedicine, Maud Kuistila, Otto Malm, and Epilepsialiitto foundations. During her Ph.D. studies, Olesia focused on cell-specific consequences of mitochondrial dysfunction in the brain. Most notably her research established astrocytes as a driver of pathology upon mitochondrial dysfunction in the brain. In our lab, Olesia uses a combination of cultured cell and mouse models to investigate the role of the mitochondrial SUMO ligase in host defense responses. Olesia’s position is currently supported by the Sigrid Juselius foundation and Redpoll Fellowships. Expertise: mitochondrial signaling, astrocyte-neuron interactions, cilogenesis, viral infection, metabolism olesia.ignatenko@mcgill.ca https://www.mcbridelab.org/camila daily 0.75 2022-01-25 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643131615797-DBQA0U37852WKWF9PQ8I/photo+camila.jpg Camila - Graduate Student Camila is a PhD student at the McGill University's Integrated Program in Neuroscience, under the co-supervision of Dr. McBride and Dr. Austen Milnerwood. Camila has a master’s degree in Biochemistry and a bachelor’s degree in Biotechnology, both at Federal University of Rio Grande do Sul (UFRGS) in Brazil. During both undergraduate and graduate research, Camila has studied mechanisms related to neuroimmune signaling involved in Parkinson’s disease. Currently, she is working on the roles of LRRK2 and Vps35 mutations in immune signaling pathways. During her PhD studies she will be looking at multiple functional outputs within primary neurons, microglia and astrocytes in conditions of inflammation to understand cell biology processes, signaling pathways and effects on neuronal function and survival. Expertise: Parkinsons disease, LRRK2, VPS35, dopaminergic neuron, lysosome, mitochondria https://www.mcbridelab.org/mt-inflammation daily 0.75 2023-01-12 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/eb4f40dd-8c9a-44b8-919f-8d04e3079734/Doiron+et+al+Sci+Rep+2017-1.jpg MT inflammation https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/2ef232d9-0c4d-494b-a04b-0f84b652005d/Mathoud+et+al+Cell+2016-1.jpg MT inflammation https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/fd2b8e9f-dbb0-4129-b48e-a57202b8c454/Matheoud+Cannon+et+al+nature+2019-1+copy.jpg MT inflammation https://www.mcbridelab.org/mt-iron daily 0.75 2023-01-12 https://www.mcbridelab.org/peroxisome-page daily 0.75 2023-01-12 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/1643226718006-CR43SYWK3U5XT3GR8ZZC/MDVPaper1.png Peroxisome page https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/49b7beb6-6bd4-40b4-b229-00f6ceb4727e/Sugiura+nature21375-2-1.jpg Peroxisome page https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/525dcb4f-5eab-4f81-b320-57cfdc3f975a/Braschi+Curr+Biol+2010-1.jpg Peroxisome page https://www.mcbridelab.org/jessica daily 0.75 2024-11-11 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/34fef3fb-e398-4522-8a1f-93c0a05583b9/Image+from+iOS.jpg https://www.mcbridelab.org/allie daily 0.75 2025-08-18 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/648df3fa-3fdd-455c-9c1b-932b1443a395/Image+from+iOS+%281%29.jpg https://www.mcbridelab.org/nico daily 0.75 2024-11-11 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/431561c1-ece4-47a5-a060-154c8a3c954f/nico https://www.mcbridelab.org/yeji daily 0.75 2025-08-18 https://images.squarespace-cdn.com/content/v1/60ede8013a20104c4ffe339b/9137851d-c330-4c43-8f86-6e6d8d77c75c/Yeji_Song.JPG